LIQMIX™ INSIDE
NEPHOS — Liquid-to-Gas Mixer
Liquid-to-Gas Standard Generator — from % to ppb
AlySoft™ software — unified control, sequences, analyzer sync and full Audit Trail.
NEPHOS is a liquid-to-gas mixer that generates precise gas-phase calibration standards directly from liquid sources — the standard solution for VOCs, alcohols, water vapour and semi-volatile compounds that are unavailable or unstable in gas cylinders. It operates standalone or combined with a GasMix™ system, controlled via AlySoft™ with full traceability and ISO 6145-7 compliance
NEPHOS — How a Liquid-to-Gas Mixer Works
NEPHOS is AlyTech’s latest evolution in the LiqMix™ range — a bench solution that produces custom gas standards directly from pure or mixed liquids. Optional cascade dilution unlocks an exceptionally wide concentration span, from percent down to ppb.
The instrument precisely vaporizes up to two liquid phases into a controlled carrier gas stream, generating mixtures on demand with full traceability. A modular architecture lets your system evolve as requirements grow — ideal for QA/QC, method development and analyzer validation.
Heated transfer paths up to the delivery point prevent re-condensation, ensuring a clean, stable gas phase for accurate, repeatable measurements.
Direct Coriolis metering — measured mass, not estimated volume
NEPHOS meters every liquid with a Coriolis mass flow meter — it measures the true mass delivered, independent of the liquid’s density, viscosity, temperature or conductivity. That means accurate, repeatable standards across pure liquids and complex mixtures alike, with no re-tuning when you change fluid.
Density-independent: Switch solvents without re-calibrating the dosing.
Real-time verification: liquid and gas flows are monitored continuously, so the produced concentration is known at every instant.
Two simultaneous liquid channels for genuine multi-component standards.
Sulfinert®-treated wetted paths for reactive and corrosive compounds.
Technical Specifications
Everything the NEPHOS delivers, at a glance.
| 💧 Liquid & Gas Channels | |
| Liquid channels | 1 or 2 (simultaneous mixing) |
|---|---|
| Liquid flow (Coriolis) | 0.5–5 g/h | 0.5–200 g/h |
| Gas channels | 1 to 6 |
| Compatible liquids | Pure liquids or liquid mixtures (water, organic solvents) — particle-free |
| Gas compatibility | Pure gases, concentrated mixtures, most aggressive gases |
| 🎯 Mixing & Dilution | |
| Concentration range | from % down to ppb |
| Dilution factor | up to 10⁸ |
| Output flow accuracy | < 2 % of measured flow * |
| Output concentration accuracy | < 2 % |
| ✓ Accuracy & Traceability | |
| Standard | ISO 6145-7 compliant |
| Calibration | MFC & Coriolis factory-calibrated, NIST-traceable |
| Metrology features | Automatic uncertainty calculation, certificate issuance, Audit Trail |
| Anti-corrosion | Sulfinert®-treated wetted paths |
| ⬦ Pressure & Connections | |
| Gas inlet pressure | stable between 3 and 8 bar(g) |
| Outlet pressure | atmospheric (higher possible) |
| Heated line | 2m heated output line standard (other lengths available) |
| Connections | Swagelok® 1/16″, 1/8″ & 1/4″ |
| ⚡ Interface & Power | |
| Software | AlySoft™ on Windows 10 or higher, Ethernet communication |
| Power supply | 90–260 VAC, 1.5–4 A, 50–60 Hz |
| ▢ Physical | |
| Dimensions (L × W × H) | 50 × 47 × 58 cm |
| Weight | 25–40 kg (depends on configuration) |
* When MFCs operate between 10 % and 100 % of full-scale flow.
Software & Automation for the NEPHOS Liquid-to-Gas System
NEPHOS combines a Coriolis-type liquid flow meter with a precisely regulated vaporization chamber. Mass Flow Controllers (MFC) deliver repeatable dilutions, while heated lines maintain the gas phase to the outlet.
Unified control of liquid and gas flows with AlySoft™ software
User-defined sequences for vaporization, dilution and calibration
Real-time monitoring, safety rules and event logging
Synchronization with GC, spectrometers and gas analyzers
Audit Trail for complete traceability
Key Benefits
On-Demand Standards
Create calibration gases from liquids and liquid mixtures, instantly.
% → ppb Coverage
Cascade dilution spans an exceptionally wide concentration range.
Coriolis Accuracy
Direct mass metering, density-independent, no re-tuning per fluid.
Traceable by Design
Automatic uncertainty, certificates and Audit Trail in AlySoft™.
Stable Gas Phase
Heated lines prevent re-condensation to the point of delivery.
Modular & Serviceable
Add liquid or gas channels and options as your needs evolve.
Applications
NEPHOS enables on-demand standards for calibration, validation and research from volatile organics to humidity and siloxanes.
Biogas & Siloxanes
Generate siloxane standards to assess silicone-related contaminants.
Filter & Sensor Testing
Ethanol/phenol vapors for carbon filter studies; humidity standards for sensor validation.
Trace VOC & Research
BTEX and other VOC mixes for LOD/LOQ, linearity and hysteresis checks.
Emissions & CEMS
Humid, reactive-compound standards for analyzer checks and validation routines.
Why choose NEPHOS for liquid-to-gas standards?
How NEPHOS compares to conventional peristaltic / syringe-pump generators.
| GasMix™NEPHOS | Pump-based generators | |
|---|---|---|
| Liquid metering | Coriolis mass flow — direct mass | Peristaltic / syringe pump — volumetric |
| Fluid change | No re-tuning (density-independent) | Often requires recalibration per fluid |
| Stated accuracy | < 2 % concentration, ISO 6145-7 | Frequently unspecified |
| Uncertainty & certificate | Auto-calculated, issued per point | Rarely provided |
| Range | % → ppb, up to 10⁸ dilution | Model-dependent |
| System | One modular, upgradable instrument | Multiple separate models |
| Humidity / water vapour | Supported — high accuracy on aqueous standards | Supported — optimized for long-run stability |
FAQ — NEPHOS
Most asked questions about liquid-to-gas standard generation, traceability and daily operation.
NEPHOS covers a very wide range, from percent-level vapors down to trace and ppb levels. When equipped with optional cascade dilution, the overall dilution factor can reach up to 108, depending on configuration and application.
NEPHOS is suitable for many organic solvents and VOC mixtures (e.g. BTEX, siloxanes, alcohols, phenols) and, in dedicated configurations, water or aqueous solutions. Final compatibility depends on volatility, viscosity and material compatibility; our team can review your liquid list and propose the appropriate configuration.
No, NEPHOS is designed to generate gas standards directly from liquids using a carrier gas. It can also be combined with existing gas standards or GasMix™ platforms when you want to mix liquid-derived components with gas-phase standards in the same stream.
Vaporization takes place in a controlled, heated chamber and the transfer path to the outlet is heated to maintain the gas phase. This minimizes the risk of condensation, especially for higher-boiling components, and improves repeatability at low concentrations.
Yes, on request NEPHOS can be built with inert-grade wetted materials (SS316, inert coatings, Kalrez® seals) for aggressive or reactive compounds. For highly corrosive or unusual chemistries, we recommend providing details so we can check material compatibility and lifetime.
NEPHOS relies on 400-point calibrated MFCs, NIST-traceable references and LiqMix™ software. The software calculates concentrations, manages sequences, logs all critical events in an Audit Trail and can generate certificates including calculated concentrations and uncertainties for QA/QC documentation.
A typical installation requires electrical power, a suitable carrier gas supply (e.g. nitrogen, air or other matrices depending on your application) and proper ventilation or exhaust according to the compounds used. Exact requirements are specified in the technical documentation.
Yes. LiqMix™ can synchronize sequences with GC, preconcentrators, spectrometers and other gas analyzers using digital I/O and timing parameters. This allows fully automated calibration routines with minimal operator intervention.
Yes. NEPHOS generates traceable, reactive-compound and humid standards suitable for analyzer checks and validation in emission-monitoring workflows. Tell us your components and regulatory framework and we’ll confirm the configuration.
NEPHOS meters liquids with a Coriolis mass flow meter, measuring true mass independent of density, viscosity or temperature — so you can change fluids without re-tuning. It states a < 2 % concentration accuracy, is ISO 6145-7 compliant, and issues a certificate with uncertainty for every point. Many peristaltic or syringe-pump generators dose by volume and do not publish an accuracy figure.
Yes. NEPHOS vaporizes water and aqueous solutions to generate humid calibration gas alongside your target compounds. Its design prioritizes certified concentration accuracy; for applications requiring very long-duration humidity stability, contact us to confirm the right configuration.
A Coriolis meter measures the actual mass of liquid delivered, unaffected by the fluid’s density, viscosity, temperature or conductivity. This means accurate, repeatable standards across different solvents and mixtures without recalibrating the dosing each time you change liquid — an advantage volumetric pumps cannot match.
Ready to Generate Standards on Demand?
Bring traceable liquid-to-gas calibration to your bench powered by AlySoft.